Hypopituitarism | Symptoms


What are the symptoms of hypopituitarism?

The symptoms of hypopituitarism usually develop gradually, although it is possible for them to appear suddenly. Because the symptoms tend to progress over time, they are often overlooked for months or years.

Possible symptoms include:

  • Abdominal discomfort
  • Constipation
  • Facial puffiness
  • Fatigue
  • Headaches
  • Hoarse voice
  • Low blood pressure
  • Loss of appetite
  • Loss of underarm and pubic hair
  • Muscle weakness
  • Nausea
  • Sensitivity to cold or difficulty staying warm
  • Stiffness in the joints
  • Thirst and excessive urination
  • Unintended weight loss or gain
  • Vision problems

Men may also experience:

  • Erectile dysfunction
  • Decrease in facial or body hair
  • Loss of interest in sexual activity

Women may also experience:

  • Inability to produce milk for breast-feeding
  • Infertility
  • Irregular or stopped menstrual periods

Children may also experience:

  • Stunted growth, which may result in short stature
  • Slowed sexual development

If certain symptoms of hypopituitarism develop suddenly, such as a severe headache, visual problems, confusion, or a drop in blood pressure, you should see a doctor immediately. These symptoms could be a sign of sudden bleeding into the pituitary (called pituitary apoplexy), which is a serious condition.

Written by familydoctor.org editorial staff

Reviewed/Updated: 03/14
Created: 09/07