Interstitial Nephritis | Causes & Risk Factors


What causes interstitial nephritis?

Interstitial nephritis can be caused by the following problems:

  • Infections
  • A reaction to a medicine, such as certain antibiotics
  • Too much of certain medicines (pain relievers, such as acetaminophen, aspirin or a non-steroidal anti-inflammatory drug [NSAID], or diuretics [water pills])

Interstitial nephritis may occur 2 or more weeks after you start a medicine. Talk to your doctor if you have any questions about a medicine you are taking.


Diagnosis and Management of Acute Interstitial Nephritis by CM Kodner, M.D. and A Kudrimoti, M.D. (American Family Physician June 15, 2003,

Written by editorial staff

Reviewed/Updated: 03/14
Created: 12/04