What causes mastocytosis?
Doctors don't know exactly why some people have too many mast cells. Some of the things that trigger the release of histamine from mast cells also cause the symptoms of mastocytosis. Symptoms may be triggered by cold or heat, certain medicines, emotional stress and insect bites. However, the triggers aren't the same in every person.
Cutaneous and Systemic Manifestations of Mastocytosis by WA Alto, M.D., M.P.H., and L Clarcq, D.O. (American Family Physician June 01, 1999, http://www.aafp.org/afp/990600ap/3047.html)
Written by familydoctor.org editorial staff