High Cholesterol | Cholesterol-lowering Medicines

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Learn More About High Cholesterol Treatment

Lifestyle Changes to Lower Your Cholesterol

Plant Sterols and Stanols

Why did my doctor prescribe cholesterol-lowering medicine for me?

Lowering your "bad" cholesterol (also called LDL, or low-density lipoprotein) can reduce your risk of having a heart attack or stroke. A number of lifestyle changes can help you improve your cholesterol level. However, if these lifestyle changes don't help after about 6 months to 1 year, your doctor may suggest medicine to lower your cholesterol.

Even if you take cholesterol-lowering medicine, it's important to keep up with your lifestyle changes. Eating a healthy diet and being physically active can make your medicine more effective. Your doctor can give you tips on how to make healthy food choices and include physical activity in your daily routine.

What are some common cholesterol-lowering medicines?

Several types of medicine are used to treat high cholesterol levels. Your doctor will decide which type of medicine is right for you. He or she may prescribe more than 1 of these drugs at a time because combinations of these medicines can be more effective.

Statins (also called HMG-CoA reductase inhibitors) slow down your body's production of cholesterol. These drugs also remove cholesterol buildup from your arteries (blood vessels).

Resins (also called bile acid sequestrants) bind to bile acids. Bile acids help with digestion, and are made by your liver using cholesterol. When resins bind to the bile, the body gets rid of them. This prompts your body to use excess cholesterol to make more bile acids. This lowers your LDL cholesterol level.

Cholesterol absorption inhibitors help lower your cholesterol by reducing the amount that is absorbed by your intestines. This type of medicine is often given in combination with a statin.

Fibrates (also called fibric acid derivatives) help lower your cholesterol by reducing the amount of triglycerides (fats) in your body and by increasing your level of "good" cholesterol (also called HDL, or high-density lipoprotein).

Niacin (also called nicotinic acid) is a B vitamin. When given in large doses, it can lower your levels of triglycerides and LDL cholesterol, and increase your HDL cholesterol level. Even though you can buy niacin without a prescription, over-the-counter niacin is not effective in lowering cholesterol and can have harmful side effects on your liver. You should only take niacin that your doctor prescribes for you.

Do cholesterol-lowering medicines have any side effects?

Like all medicines, these drugs can cause side effects. However, the side effects usually are not severe and are not experienced very often.

Common side effects of cholesterol-lowering drugs include the following:

  • Diarrhea or constipation
  • Abdominal pain, cramps, bloating or gas
  • Nausea
  • Vomiting
  • Headache
  • Drowsiness
  • Dizziness
  • Muscle aches or weakness
  • Flushing (skin turning red and warm)
  • Sleep problems

Tell your doctor as soon as possible if your side effects become severe.

What is a drug interaction?

If you take 2 or more medicines at the same time, the way your body processes each drug can change. When this happens, the risk of side effects from each drug increases and each drug may not work the way it should. This is called a "drug-drug interaction." Vitamins and herbal supplements can also affect the way your body processes medicine.

Certain foods or drinks can also prevent your medicine from working the way it should or make side effects worse. This is called a "drug-food interaction."

Drug-drug interactions and drug-food interactions can be dangerous. Be certain that your doctor knows all of the over-the-counter and prescription medicines, vitamins and herbal supplements that you are taking. Also, talk to your doctor before you take any new over-the-counter or prescription medicine, or use a vitamin or herbal supplement.

It's important to take medicines exactly as your doctor tells you to. Ask your doctor whether you need to avoid any foods or drinks while using your cholesterol-lowering medicine.

Written by familydoctor.org editorial staff

Reviewed/Updated: 01/11
Created: 09/04

Learn More About High Cholesterol Treatment

Lifestyle Changes to Lower Your Cholesterol

Plant Sterols and Stanols

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